Microbial metabolite repairs liver injury by restoring hepatic lipid metabolism

63 PaulHoule 5 8/28/2025, 11:29:42 AM journals.asm.org ↗

Comments (5)

mmmpetrichor · 2h ago
I'll drink to that!
DaveZale · 1h ago
kefir has that microbe. So drink some kefir

and eat a kraut dog. Or a Ruben. https://en.m.wikipedia.org/wiki/Lactiplantibacillus_plantaru...

searine · 3h ago
Supported by grants from NIH/NIAID Grants and the University of California Davis.
DaveZale · 1h ago
yeah Davis is agriculturally oriented. Because this microbe grows in cows stomachs it is added to silage (feed) - so dairy products have this metabolite.

Amazing finding. The statistics on liver damage from aflatoxins said to affect potentially 5 billion people. And of course in the US, with its high incidence of obesity has liver issues due to NAFLD. Then of course the heavy drinkers are all at risk.

ck2 · 38m ago
10-HSA is a fatty-acid metabolite produced by Lactobacillus bacteria

Lactobacillus Plantarum is a super common probiotic that produces 10-HSA and other important metabolites

its commercial name is also known as lp299v which has been studied for decades, tons of studies

for example: https://www.mdpi.com/2073-4344/10/2/154

lp299v is extreme safe and can be taken in mega-doses however it will not colonize in the GI so would have to be taken routinely