Show HN: ARR-Medic-CYP3A4 – Open-Source Drug Interaction Toolkit

1 Flamehaven01 0 9/17/2025, 1:08:25 PM github.com ↗

Arr-Medic-CYP3A4 is an open-source Python toolkit for modeling CYP3A4-mediated drug interactions.

Key features

- ~70% accuracy baseline for research & learning - Transparent, extensible codebase (RDKit, ML, GNN roadmap) - Safe "sandbox" for experimenting with drug metabolism prediction - Reproducible and community-driven Open source → research/teaching now, bridge to clinical-grade systems later.

Repo: https://github.com/Flamehaven/Arr-Medic-CYP3A4

Try the live demo here: https://huggingface.co/spaces/Flamehaven/arr-medic-cyp3a4-de... Read how it all began: "My First Attempt at a Medical AI with ELI5" on Medium: https://medium.com/p/ccc0edbd2bce

Feedback welcome: How do you think such tools could be responsibly used or improved?

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Show HN: ARR-Medic-CYP3A4 – Open-Source Drug Interaction Toolkit

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