Some forms of autism are highly inheritable. Asperger's Syndrome is inheritable at a rate of about 80%. In these cases the cause is genetic, but genetics is likely only one of many potential causes.
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nis0s · 1h ago
It occurs to me that pain killers can cross the placenta and also affect gut microbes, and that since sometimes autism isn’t inherited, there’s a gut microbe imbalance component to autism that needs more attention, especially related to how gut microbes differ in those born with and without Caesarians. Secondly, how are genes related to autism also linked to the gut-brain axis.
Gut health isn’t mentioned in the article, so it seems like a good point to bring up.
mikestew · 54m ago
You’re not saying Tylenol causes autism, are you?
nis0s · 44m ago
I am saying it’s possible there’s a gut-brain axis being affected by any number of factors. Consider Caesarian babies. I didn’t look it up, but I think since Caesarian babies aren’t exposed to bacteria from the vaginal canal, it perhaps contributes to their condition.
RAM-bunctious · 3m ago
It's technically possible that early-life microbiome differences from bypassing the birth canal could influence it, but the fact that the association disappears when siblings who were delivered differently are compared is suggestive.
Gut health isn’t mentioned in the article, so it seems like a good point to bring up.
"However, the association did not persist when using sibling controls, implying that this association is due to familial confounding by genetic and/or environmental factors." - https://jamanetwork.com/journals/jamapsychiatry/fullarticle/...