Third patient dies from acute liver failure caused by a Sarepta gene therapy (biocentury.com)

99 points by randycupertino 2h ago 22 comments

Asynchrony Is Not Concurrency (kristoff.it)

39 points by kristoff_it 1h ago 15 comments

AI CapEx Is Eating the Economy (paulkedrosky.com)

24 points by throw0101c 29m ago 2 comments

Replication of Quantum Factorisation Records with a VIC-20, an Abacus, and a Dog (eprint.iacr.org)

30 points by teddyh 1h ago 4 comments

Show HN: I built library management app for those who outgrew spreadsheets (librari.io)

12 points by hmkoyan 59m ago 4 comments

lsr: ls with io_uring (rockorager.dev)

257 points by mpweiher 7h ago 144 comments

Trying Guix: A Nixer's impressions (tazj.in)

102 points by todsacerdoti 3d ago 24 comments

CP/M creator Gary Kildall's memoirs released as free download (spectrum.ieee.org)

204 points by rbanffy 10h ago 102 comments

Cancer DNA is detectable in blood years before diagnosis (sciencenews.org)

64 points by bookofjoe 1h ago 24 comments

Mango Health (YC W24) Is Hiring (ycombinator.com)

1 points by zachgitt 1h ago 0 comments

Benben: An audio player for the terminal, written in Common Lisp (chiselapp.com)

22 points by trocado 3d ago 1 comments

The Year of Peak Might and Magic (filfre.net)

18 points by cybersoyuz 3h ago 2 comments

How I keep up with AI progress (and why you must too) (blog.nilenso.com)

92 points by itzlambda 1h ago 58 comments

I'm Peter Roberts, immigration attorney who does work for YC and startups. AMA

131 points by proberts 5h ago 207 comments

Section 174 is reversed! Mostly, that is. (newsletter.pragmaticengineer.com)

78 points by jawns 2h ago 34 comments

Hundred Rabbits – Low-tech living while sailing the world (100r.co)

186 points by 0xCaponte 4d ago 47 comments

When root meets immutable: OpenBSD chflags vs. log tampering (rsadowski.de)

123 points by todsacerdoti 11h ago 41 comments

LibreOffice slams Microsoft for locking in Office users w/ complex file formats (neowin.net)

105 points by bundie 3h ago 64 comments

A New Geometry for Einstein's Theory of Relativity (quantamagazine.org)

26 points by jandrewrogers 5h ago 0 comments

How to Get Foreign Keys Horribly Wrong (hakibenita.com)

30 points by Bogdanp 3d ago 8 comments

HathiTrust Digital Library (hathitrust.org)

51 points by djoldman 3d ago 15 comments

CoCo1 composite video (leadedsolder.com)

22 points by zdw 3d ago 1 comments

The Art of Roland-Garros (garros.gallery)

52 points by pentagrama 3d ago 4 comments

DHS: Filming Cops, ICE Officers Is a 'Violent Tactic' (techdirt.com)

66 points by mdhb 1h ago 19 comments

Dear valued user, You have reached the error page for the error page (imgur.com)

150 points by Alex3917 4h ago 33 comments

Psilocybin decreases depression and anxiety in cancer patients (2016) (pmc.ncbi.nlm.nih.gov)

234 points by Bluestein 9h ago 226 comments

The Israeli "art student" mystery (2002) (salon.com)

65 points by georgecmu 2h ago 12 comments

Exposed MCP servers across the internet (knostic.ai)

65 points by gepeto42 6h ago 26 comments

Row Polymorphic Programming (stranger.systems)

43 points by todsacerdoti 4d ago 25 comments

Firefox-patch-bin, librewolf-fix-bin AUR packages contain malware (lists.archlinux.org)

86 points by rrampage 2h ago 77 comments

Ask HN: Any active COBOL devs here? What are you working on?

212 points by _false 7h ago 160 comments

15 Years of Building Jefit (jefit.com)

48 points by jasong 3d ago 29 comments

Ring reintroduces video sharing with police (theverge.com)

7 points by 01-_- 1h ago 2 comments

Inspect ANSI control codes and escape sequences (ansi.tools)

95 points by webpro 3d ago 47 comments

Fully homomorphic encryption and the dawn of a private internet (bozmen.io)

397 points by barisozmen 16h ago 184 comments

Microsoft Confirms the Closure of Its Underwater Data Center (extremetech.com)

5 points by Bluestein 21m ago 2 comments

Ask HN: GCP Outage?

78 points by grilledchickenw 5h ago 35 comments

Coldplay kiss-cam flap proves we're our own surveillance state (theregister.com)

6 points by rntn 1h ago 0 comments

Experts lay into Tesla safety in federal autopilot trial (arstechnica.com)

23 points by duxup 2h ago 5 comments

Jandas: A much Pandas-like JavaScript library for data science (github.com)

5 points by mmarian 1h ago 0 comments

Matt Dillon discusses the past, present and future of BSDs (2022) (web.archive.org)

3 points by cnst 34m ago 0 comments

DIY Telescope Mods That Transformed My Astrophotography (youtube.com)

71 points by karlperera 3d ago 16 comments

TCP-in-UDP Solution (eBPF) (blog.mptcp.dev)

75 points by todsacerdoti 3d ago 19 comments

Getting off US tech: a guide (disconnect.blog)

6 points by DoctorOW 1h ago 1 comments

ICE is getting unprecedented access to Medicaid data (wired.com)

215 points by josefresco 5h ago 226 comments

DuckDuckGo now lets you hide AI-generated images in search results (techcrunch.com)

134 points by moose44 3h ago 52 comments

My favorite use-case for AI is writing logs (newsletter.vickiboykis.com)

242 points by todsacerdoti 20h ago 172 comments

Extending That XOR Trick to Billions of Rows (nochlin.com)

93 points by hundredwatt 4d ago 17 comments

OpenAI: A $50M fund to build with communities (openai.com)

4 points by OutOfHere 58m ago 1 comments

NIH is cheaper than the wrong dependency (lewiscampbell.tech)

282 points by todsacerdoti 18h ago 183 comments

macOS Tahoe's Folder Icon Customization

1 mpweiher 0 7/18/2025, 1:29:56 PM mjtsai.com ↗

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