Artificial sweeteners can harm cognitive health equivalent to 1.6 years of aging

6 OutOfHere 4 9/5/2025, 2:13:12 AM theguardian.com ↗

Comments (4)

OutOfHere · 18h ago
Study: https://www.neurology.org/doi/10.1212/WNL.0000000000214023

From the abstract:

> Consumption of aspartame, saccharin, acesulfame k, erythritol, sorbitol, and xylitol was associated with a faster decline in global cognition, particularly in memory and verbal fluency domains.

These findings do NOT apply to tagatose, stevia, or mogroside.

Terr_ · 18h ago
> These findings do NOT apply to tagatose, stevia, or mogroside

I think it's important to call out the difference between "did not find a correlation" versus "did not look".

Tagatose is listed as part of their questionnaire, but not stevia or mogroside.

> these are natural sweeteners

Xylitol is also a natural sweetener, so it is at best premature to adopt a natural-versus-unnatural framing from these results.

Centrino · 11h ago
What about sucralose, another widely used artificial sweetener?
OutOfHere · 10h ago
Avoid it because it disrupts the gut microbiota to harm immune cell function. Refer to https://doi.org/10.1158/2159-8290.CD-25-0247