The Windows Subsystem for Linux is now open source (blogs.windows.com)

1539 points by pentagrama 1d ago 1139 comments

Baby is healed with first personalized gene-editing treatment (nytimes.com)

1248 points by jbredeche 5d ago 529 comments

AlphaEvolve: A Gemini-powered coding agent for designing advanced algorithms (deepmind.google)

1030 points by Fysi 6d ago 268 comments

Coding without a laptop: Two weeks with AR glasses and Linux on Android (holdtherobot.com)

1006 points by mikenew 6d ago 383 comments

Spaced repetition systems have gotten better (domenic.me)

989 points by domenicd 2d ago 498 comments

Have I Been Pwned 2.0 (troyhunt.com)

826 points by LorenDB 1d ago 279 comments

What is HDR, anyway? (lux.camera)

803 points by _kush 6d ago 337 comments

Zod 4 (zod.dev)

756 points by bpierre 1d ago 246 comments

Human (quarter--mile.com)

730 points by surprisetalk 6d ago 270 comments

Thoughts on thinking (dcurt.is)

701 points by bradgessler 4d ago 435 comments

Don't guess my language (vitonsky.net)

651 points by e-topy 1d ago 359 comments

DDoSecrets publishes 410 GB of heap dumps, hacked from TeleMessage (micahflee.com)

644 points by micahflee 1d ago 180 comments

Veo 3 and Imagen 4, and a new tool for filmmaking called Flow (blog.google)

618 points by youssefarizk 15h ago 361 comments

France Endorses UN Open Source Principles (social.numerique.gouv.fr)

606 points by bzg 2d ago 210 comments

Push Ifs Up and Fors Down (matklad.github.io)

558 points by goranmoomin 3d ago 197 comments

GitHub Copilot Coding Agent (github.blog)

541 points by net01 1d ago 354 comments

Making video games (without an engine) in 2025 (noelberry.ca)

518 points by selvan 1d ago 229 comments

Ground control to Major Trial (virtualize.sh)

517 points by plam503711 4d ago 190 comments

Jules: An asynchronous coding agent (jules.google)

511 points by travisennis 1d ago 222 comments

A Research Preview of Codex (openai.com)

507 points by meetpateltech 4d ago 445 comments

Bus stops here: Shanghai lets riders design their own routes (sixthtone.com)

493 points by anigbrowl 7d ago 362 comments

Getting AI to write good SQL (cloud.google.com)

492 points by richards 4d ago 353 comments

Proton threatens to quit Switzerland over new surveillance law (techradar.com)

487 points by taubek 3d ago 218 comments

I don't like NumPy (dynomight.net)

486 points by MinimalAction 5d ago 205 comments

InventWood is about to mass-produce wood that's stronger than steel (techcrunch.com)

469 points by LorenDB 2d ago 422 comments

Ditching Obsidian and building my own (amberwilliams.io)

461 points by williamsss 2d ago 537 comments

Writing that changed how I think about programming languages (bernsteinbear.com)

458 points by r4um 7d ago 60 comments

Flattening Rust’s learning curve (corrode.dev)

456 points by birdculture 7d ago 397 comments

Claude Code SDK (docs.anthropic.com)

442 points by sync 1d ago 191 comments

The unreasonable effectiveness of an LLM agent loop with tool use (sketch.dev)

442 points by crawshaw 5d ago 319 comments

Finland announces migration of its rail network to international gauge (yle.fi)

441 points by axelfontaine 1d ago 414 comments

Mystical (suberic.net)

433 points by mmphosis 3d ago 45 comments

Dilbert creator Scott Adams says he will die soon from same cancer as Joe Biden (thewrap.com)

431 points by dale_huevo 1d ago 547 comments

A leap year check in three instructions (hueffner.de)

431 points by gnabgib 5d ago 164 comments

Coinbase says hackers bribed staff to steal customer data, demanding $20M ransom (cnbc.com)

420 points by gpi 5d ago 499 comments

Deep Learning Is Applied Topology (theahura.substack.com)

413 points by theahura 19h ago 165 comments

The recently lost file upload feature in the Nextcloud app for Android (nextcloud.com)

413 points by morsch 7d ago 166 comments

Game theory illustrated by an animated cartoon game (ncase.me)

411 points by felineflock 1d ago 67 comments

SMS 2FA is not just insecure, it's also hostile to mountain people (blog.stillgreenmoss.net)

411 points by todsacerdoti 6d ago 314 comments

A server that wasn't meant to exist (it-notes.dragas.net)

404 points by jaypatelani 6d ago 146 comments

Databricks acquires Neon (databricks.com)

387 points by davidgomes 6d ago 225 comments

MIT asks arXiv to withdraw preprint of paper on AI and scientific discovery (economics.mit.edu)

384 points by carabiner 4d ago 200 comments

Show HN: I modeled the Voynich Manuscript with SBERT to test for structure (github.com)

379 points by brig90 2d ago 129 comments

Malicious compliance by booking an available meeting room (clientserver.dev)

374 points by jakevoytko 5d ago 367 comments

LLMs get lost in multi-turn conversation (arxiv.org)

372 points by simonpure 6d ago 255 comments

After months of coding with LLMs, I'm going back to using my brain (albertofortin.com)

360 points by a7fort 4d ago 220 comments

AniSora: Open-source anime video generation model (komiko.app)

353 points by PaulineGar 3d ago 216 comments

Japan's IC cards are weird and wonderful (aruarian.dance)

353 points by aecsocket 5d ago 293 comments

Ollama's new engine for multimodal models (ollama.com)

352 points by LorenDB 5d ago 84 comments

If nothing is curated, how do we find things (tadaima.bearblog.dev)

351 points by nivethan 3d ago 252 comments

Schrödinger lays off 60 amid uncertain times and challenging economic conditions

3 randycupertino 2 5/20/2025, 10:21:06 PM fiercebiotech.com ↗

Comments (2)

ggm · 10h ago

There are rare moments when a headline writes itself but if you were looking for one..

> Schrödinger [...] uncertain [...]

would have to be right up there.

randycupertino · 10h ago

NYC-based drug discovery startup that tried to use software modeling. Also worth noting that the CFO was forced out.