The Power of CICO

2 paulpauper 1 8/25/2025, 6:07:23 PM twitter.com ↗

Comments (1)

zahlman · 4h ago
All of this is well understood and I think not particularly disputed. It is the basis for example of https://www.fourmilab.ch/hackdiet/ (RIP John Walker). For serious people, the debate revolves around the feasibility of actually restricting caloric intake, with a side discussion of whether macro composition can significantly influence metabolism.