Lower risk of dementia with AS01-adjuvanted vaccination

Comments (2)

tomsto · 4h ago

AS01-adjuvanted shingles (herpes zoster) vaccination is associated with a lower risk of dementia, but the underlying mechanisms are unclear. In propensity-score matched cohort studies with 436,788 individuals, both the AS01-adjuvanted shingles and respiratory syncytial virus (RSV) vaccines, individually or combined, were associated with reduced 18-month risk of dementia. No difference was observed between the two AS01-adjuvanted vaccines, suggesting that the AS01 adjuvant itself plays a direct role in lowering dementia risk.

fithisux · 4h ago

If the underlying mechanism is unclear, we definitely need many more studies to replicate the effect.

Illinois Vehicle Mileage Tax–Fix the Roads and Fund the Future (forbes.com)

Show HN: I built a tool to save and manage AI prompts on my local device (github.com)

Show HN: Tomatic – openrouter AI chat interface (github.com)

The iPad Is About to Become a Much Better Video Editor (petapixel.com)

How One Million Chessboards Works (eieio.substack.com)

Show HN: An AI agent that debugs your LLM app and submits pull requests (github.com)

Vite 7.0 (vite.dev)

Show HN: Joyspace AI Clips – Automatically Create Short Clips from Long Videos

AI May Be Underhyped (barrons.com)

Google Cloud Donates A2A to Linux Foundation (developers.googleblog.com)

Why Single-Tenant Applications Are Better Than Multi-Tenant SaaS (fusionauth.io)

We Should Be Taking a Minimum of Two Showers a Day in the Summer (gq.com)

Why HS2 cost so much (martinrobbins.substack.com)

Show HN: An App that turns your phone into a tour guide (tripoclock.com)

Games Run Faster on SteamOS Than Windows 11, Ars Testing Finds (games.slashdot.org)

Show HN: LuxWeather – ad-free pixel art weather site made with asp.net and Htmx (luxweather.com)

Federated Credential Management (FedCM) API (developer.mozilla.org)

Use artifacts to visualize and create AI apps without ever writing code (support.anthropic.com)

Fear of deployments is the largest tech debt (aviator.co)

Restmail – sendmail-compatible CLI for Gmail and outlook (github.com)

Shifting Forces: The Evolving Debate Around Dark Energy (undark.org)

Aaron Sorkin's The Social Network sequel officially in development (theguardian.com)

CUDA Ray Tracing 2x Faster Than RTX: My CUDA Ray Tracing Journey (karimsayedre.github.io)

Spatial learning circuitry fluctuates in step with estrous cycle in mice (thetransmitter.org)

Alijah Arenas on Cybertruck crash: 'Fighting time' to escape (espn.com)

The Fastest Motorcycle Hearse in the World (motorcyclefunerals.com)

Joey Swoll, gymcreeps and trolling: inside the TikTok workout wars (2023) (gq-magazine.co.uk)

"Nobody Expected This": Earth's Rotation Will Speed Up in July and August (iflscience.com)

Show HN: Bringing back Snacklish (via a bunch of prior samples and iteration) (github.com)

Nvidia Ruffles Tech Giants with Move into Cloud Computing (wsj.com)

Matter vs. Force: Why There Are Two Types of Particles (quantamagazine.org)

Meta Beats Copyright Suit from Authors over AI Training on Books (news.bloomberglaw.com)

Show HN: Towards agentic Graph RAG: Enhancing graph retrieval with vector search (blog.kuzudb.com)

Coding in a Material World (deadsimpletech.com)

CLI coding agents battle royale (twitter.com)

Vibe Coding Showcase: 12 Projects Built by Everyday People (kp.substack.com)

Twin Cities grocers facing disruptions in cyberattack on major distributor (startribune.com)

Running large language models at home with Ollama (chrisbeckman.dev)

ZKsync's Airbender Helps Prove Ethereum Blocks in Under 35 Seconds on Single GPU (unchainedcrypto.com)

How to find a job in tech in 2025 (vibeinterview.com)

Show HN: Deglaze Me – A Chrome extension to strip the sycophancy from ChatGPT (github.com)

Show HN: Delfyn, AI Agent to help businesses get paid faster (delfyn.co)

Anthropic destroyed millions of print books to build its AI models (arstechnica.com)

US Warns of Rising Iranian Cyberattack Threats (digitrendz.blog)

Thought Anchors: Which LLM Reasoning Steps Matter? (arxiv.org)

Microplastic contaminations in a set of beverages sold in France (sciencedirect.com)

Is the US Stock Market open? (is-market-open.com)

Satya Nadella: Microsoft's AI Bets, Hyperscaling, Quantum Breakthroughs [video] (youtube.com)

Iran is Losing the Fight to Turn Off Starlink Satellites (bloomberg.com)

40k-year-old mammoth tusk boomerang is oldest in Europe (livescience.com)

Lower risk of dementia with AS01-adjuvanted vaccination

Comments (2)