Show HN: AlphaFold 3 runs on Tenstorrent Wormhole now

1 molli 0 5/17/2025, 5:34:50 PM github.com ↗

Boltz-1 is an improved version of AlphaFold 3 that is fully open-source. TT-Boltz is my Boltz-1 fork that runs on a single Tenstorrent Wormhole card.

The goal is to free biotech from complex hardware, proprietary software and dependence on a monopoly.

Current runtime:

  - AMD Ryzen 5 8600G: ~45 minutes
  - Tenstorrent Wormhole n300: ~10 minutes
  - Nvidia T4: ~9 minutes
  - Nvidia RTX 4090: ~2 minutes

We didn't even start writing low-level code yet and Tenstorrent Blackhole was just released. I'm confident we'll get to 2 minutes.

I build in public on X: https://x.com/moritzthuening

Show HN: Blacklight – secret scanner for code, databases, drives, and Slack (github.com)

FreeBSD 14.3 Beta 3 ships with KDE Plasma 6 (neowin.net)

Tinder cuts 13% staff in latest bid to reverse declines (bloomberg.com)

AISiteBot: Business AI Chatbots (aisitebot.com)

AI-Driven Software: Why a Strong CI/CD Foundation Is Essential (thenewstack.io)

Antiqua Et Nova. Note on the Relationship Between AI and Human Intelligence (vatican.va)

Ask HN: Examples of AMP sites showing original URL after Google click?

Objcurses – ncurses 3D object viewer using ASCII in console (github.com)

'Ice,' 'Ogle' and other crypto millionaires who bought a night with Trump (washingtonpost.com)

agent.md vs agents.md (twitter.com)

Show HN: I built a community job matching platform for kids with my teenagers (jobmat.ch)

Trump warns Walmart: Don't raise prices due to my tariffs (apnews.com)

Mary Queen of Scots Channel Anamorphosis, a 3D Simulation (charlespetzold.com)

Deepseek Powered Application Builder (huggingface.co)

How AI Like ChatGPT and Perplexity Are Changing Search Engines (wilnickmagazine.com)

Is the University of Austin Betraying Its Founding Principles? (quillette.com)

Mystical (suberic.net)

Lufthansa plane flown by autopilot after pilot faints in cockpit (scmp.com)

New 'Defendnot' tool tricks Windows into disabling Microsoft Defender (bleepingcomputer.com)

Agentic Fear, Ambition and Beliefs

Largest database of nanosatellites, over 4400 nanosats and CubeSats (nanosats.eu)

What Is the Red Bead Experiment? (maaw.info)

What is this thing, called swing? (2016) (web.archive.org)

Welcome to the OSPO Book (ospobook.todogroup.org)

Gold rush moves closer to Amazon's second-tallest tree (news.mongabay.com)

Hackers Access Windows SMB Shares [video] (youtube.com)

Is current state of querying on observability data broken?

EU-backed surveillance software for detecting CSAM has flaws,manufacturer admits (ftm.eu)

Ask HN: Thoughts on companies hiring autonomous AI agents? (ycombinator.com)

I would love to work with you (robconery.com)

The Dawn of Liquid Content (genarrative.substack.com)

Dead Stars Don't Radiate (johncarlosbaez.wordpress.com)

Rust 1.87.0 and ten years of Rust (blog.rust-lang.org)

Show HN: Simple Transformer Implementation in PyTorch (github.com)

FBI Agent Goes Public with Russian Intelligence Op That Hooked Musk and Thiel (kyivpost.com)

Vibe Coding Is Metaprogramming (blog.valentin.sh)

Dakar-Djibouti (1931-1933): Counter Investigations [pdf] (quaibranly.fr)

Startups want to revive the zeppelin as the future of air travel (washingtonpost.com)

Direct Evidence for R-Process Nucleosynthesis from Giant Flare (iopscience.iop.org)

Major painpoints of Android development as a side activity – Part 1 Gradle (androidauthority.dev)

A metaverse based digital preservation of temple architecture and heritage (nature.com)

RFC 8152 – CBOR Object Signing and Encryption (COSE) (datatracker.ietf.org)

Ask HN: AI Product Bootcamp / Accelerators – Worth it or a new scam?

Looking for co-founder to solve distribution – email me sales@petlovefun.com (petlovefun.com)

A Bias Towards Action (ruminate.bearblog.dev)

Show HN: AlphaFold 3 runs on Tenstorrent Wormhole now (github.com)

The tech stack for production AI agents (decodingml.substack.com)

Alarming gains in face reconstruction from biometric templates (biometricupdate.com)

Silicon Valley's New Hold on Washington (wsj.com)

Hwacha: Ancient Korea Invented a Rocket Launcher in the 15th Century (utubepublisher.in)

Show HN: AlphaFold 3 runs on Tenstorrent Wormhole now

Comments (0)