Will protein design tools solve the snake antivenom shortage?

30 sebg 12 5/8/2025, 12:05:26 PM owlposting.com ↗

Comments (12)

karmakaze · 2h ago
Or one man with more than 200 bites and more than 700 injections of venom he prepared from some of the world's deadliest snakes[0].

[0] https://www.bbc.com/news/articles/cr5d0l7el36o

JTbane · 1h ago
Anyone else find it hilarious that snake bites follow the logic of "expose yourself to just a little deadly poison to gain immunity"?
jjtheblunt · 1h ago
Why? It's immunologically sensible : let the immune system train antibodies on a non lethal amount of novel protein antigen, like traditional vaccines, and (i bet to your point) in stark contrast with "homeopathy" in some definitions.
worthless-trash · 2h ago
A man called "Ram Chandra" used to come to my school in the 80-90's and educate us on the danger of snakes (he has since passed away).

There is a little talk of it here https://www.mackayandwhitsundaylife.com/article/remembering-...

I had seen him get bitten by a bunch of different snakes during his time demonstrating dangerous animals to my school on different occasions, he was always very kind and educational.

I believe he had was also involved in milking snakes and making antivenom, but the specifics evade me.

I believe he went to many different schools educating the small townships of the Australian outback (Imagine more than 20 less than 30) and always had time to answer my stupid questions as a child.

This part of my local culture will be missed.

thorin · 1h ago
It doesn't mention if he died from snake bites... Sounds like an interesting guy!
HarHarVeryFunny · 1h ago
I recently watched this YouTube documentary about a Borneo tribe, barely clinging onto their traditional ways/knowledge (displaced by the logging industry) who used a plant as a supposedly universal snake bite remedy ... I wonder if there was ever a scientific study of how effective it actually is?

https://www.youtube.com/watch?v=TiQBTesZUJQ

gilleain · 2h ago
User23 · 1h ago
The shortage is already rather artificial. A snakebite treatment that costs $150k in the USA is just a few hundred dollars in Mexico.
snowwrestler · 1m ago
Does it actually cost $150k, or is that just the sticker price? What does United Healthcare pay for a dose? That’s the actual price.

Fake price tags are a huge issue in health care policy.

__MatrixMan__ · 18m ago
Is your second sentence supposed to be evidence of your first?

I'm no fan of a system that prices things differently based on how much the dying person (or their insurance) is likely to be able to pay, but in such a system you've got prices dictated by demand... can you really reason your way from prices back to notions of authentic supply?

fallingknife · 8m ago
You have to deregulate the supply. Right now you have to be specifically approved to manufacture a drug. This causes monopolies / oligopolies even in non-patented medications. It should be changed to a system where any company who wants can manufacture any drug as long as it meets purity and dosage accuracy standards.
bob_theslob646 · 23m ago
How is that possible?