MRNA therapies have such high potential, there really ought to be much more public education and outreach to prevent people falling down the quackery rabbit hole. I don't just say that to pile on to the quacks. It's so detrimental and costs so many lives that it's probably a target for influence by adversary nation actors.
dpe82 · 2h ago
If we hadn't had a pandemic in which lots of people lost their collective minds and an irresponsible political machine that took advantage of that, mRNA would be pretty universally hailed as the miracle it is.
That aside, yes. Education is important. Sadly at least in the US some of the people who lost their minds are now in charge of such education.
chasil · 2h ago
This article asserts that white blood cells are the target, but we also know that (within the brain) astrocytes and [iirc] microglia can bear latent infection.
Is such a carrier capable of addressing latent reservoirs inside the blood-brain barrier? Can it cross the barrier, pervade the cerebrospinal fluid, then penetrate all infected cells?
White blood cells are a fantastic achievement, but far from the whole story.
the_real_cher · 2h ago
Lobotomy's were viewed to have so much high potential back in the day that they won the Nobel prize.
In true scientific fashion both sides would ideally just stick with the facts.
hobs · 36m ago
There's no "both sides" in science.
sroussey · 4h ago
I wonder if this can be used for other latent viruses that embed in cells like herpes and chickenpox/shingles.
stephen_g · 58m ago
Yeah, latent EBV would be great too since it seems to be one of the main causes of MS.
I believe this is already being researched with mRNA now, it would be amazing if it works out and we could treat all of these.
XorNot · 2h ago
That would be interesting because both of those have links to various late-life neurological conditions aa well.
That aside, yes. Education is important. Sadly at least in the US some of the people who lost their minds are now in charge of such education.
Is such a carrier capable of addressing latent reservoirs inside the blood-brain barrier? Can it cross the barrier, pervade the cerebrospinal fluid, then penetrate all infected cells?
White blood cells are a fantastic achievement, but far from the whole story.
In true scientific fashion both sides would ideally just stick with the facts.
I believe this is already being researched with mRNA now, it would be amazing if it works out and we could treat all of these.