Show HN: UpToTrial – OSS AI agent for clinicaltrials.gov that streams custom UI

I built UpToTrial to test two ideas:

1. Equip an LLM with the right tools to navigate complex APIs (clinicaltrials.gov).

2. Stream structured UI components instead of plain markdown.

What we made:

- Backend (Python/FastAPI): wraps the clinicaltrials.gov API, exposes higher-level actions to the agent, and streams an XML-like markup.

- Frontend (React/TS): incrementally patches the partial stream and maps tags to React components (trial cards, phase progress bars, etc.) for live rendering.

Clinical-trial metadata is dense; cards and timelines surface the important bits faster than prose.

Links:

Demo: https://uptotrial.com

Code (Apache):

– Backend: https://github.com/MaterialModel/uptotrial-backend

– Frontend: https://github.com/MaterialModel/uptotrial-frontend

Next:

If there’s interest, I’ll break out the streaming-UI layer as a standalone OSS library. Feedback and PRs welcome!